The era of digital therapies is gaining traction in Germany. Since the introduction of the DiGA (digital health applications) process in 2020, over a hundred different apps and web solutions have become available on prescription. The aim is to provide evidence-based, modular support for chronic diseases, mental health issues and rehabilitation using digital tools, in line with guidelines. According to DIGA Report 2024, doctors are increasingly using DiGAs, with over one million prescriptions already issued and the market growing rapidly.
In 2025, the DiGA landscape continues to grow in both scope and sophistication, offering evidence-based, patient-centered solutions that complement traditional care – from managing chronic diseases like type 2 diabetes to addressing mental health and rehabilitation needs.
Here are 10 DiGAs changing the future of German healthcare:
Attexis | CBT-based training for ADHD management
GAIA AG develops and commercializes evidence-based digital therapeutics grounded in Cognitive Behavioral Therapy (CBT) and clinical research. The Hamburg-based company’s product attexis delivers a structured, app-based treatment program for adults with ADHD, combining psychoeducation and CBT-driven skills training to improve attention, impulse control, and everyday organization. A randomized controlled trial demonstrated that patients using attexis alongside standard care experienced significantly fewer ADHD symptoms after three months than those receiving standard care alone. As a permanently listed DiGA, attexis can be prescribed by physicians and psychotherapists and is fully reimbursed by statutory health insurers.
ORIKO | App-based therapy for adults with ADHD
ORIKO is an application for adults with ADHD. It is a prescription-only therapy app developed by MiNDNET in cooperation with Takeda Deutschland. The program guides users through a 12-week treatment combining psychoeducation with psychotherapeutic methods such as Cognitive Behavioral Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT), and Dialectical Behavior Therapy (DBT) to improve daily structure, focus, and wellbeing. Early clinical data showed improved quality of life and reduced ADHD symptoms versus control. ORIKO can be prescribed by physicians or psychotherapists and is reimbursed by statutory health insurers.
Kranus Mictera | Empowering women with incontinence therapy
Kranus Health develops evidence-based digital therapeutics in urology and offers Kranus Mictera, a prescription DiGA for women with stress, urge, or mixed incontinence. The program combines pelvic-floor exercises, bladder training, behavioral strategies, and a micturition diary with guided education to improve symptoms and quality of life - all delivered flexibly at home via app. Clinical studies report meaningful symptom improvements and enhanced patient wellbeing after usage.
eCovery | Smart rehabilitation for lower back pain
eCover, a Leipzig-based startup and SpinLab alumni, develops app-based digital therapies for musculoskeletal conditions. Its product, the eCovery Therapy App, is a certified DiGA for patients with lower back pain. The 12-week program combines personalized, video-guided exercises for mobility, strength, and relaxation with educational content and progress tracking. Adaptive algorithms tailor each training plan to the user’s recovery stage, enabling evidence-based rehabilitation from home. The app is fully reimbursed by statutory health insurers in Germany.
Elona Explore | Mental wellbeing through self-guided therapy
Elona Explore supports patients with depression by offering psychotherapeutic interventions and psychoeducational resources. The app provides over 150 multimedia tools, such as diaries, challenges, and CBT-based educational modules, helping users manage acute stress and improve emotional resilience. Designed for use while waiting for a psychotherapy slot or as an early self-help intervention, Elona Explore promotes mental health accessibility and empowerment.
Una Health | Personalized diabetes companion
Una Health, based in Hamburg, specializes in digital therapeutics for metabolic diseases. Its product Una Health for Diabetes is an approved DiGA for adults with type 2 diabetes (ICD-10 E11). The app provides structured guidance on lifestyle modification, nutrition, blood glucose monitoring, and behavioral strategies to improve glycemic control and quality of life. By integrating personalized recommendations and real-time feedback, Una Health helps patients better understand the relationship between daily habits and blood sugar levels.
Uroletics | Digital recovery after prostate surgery
Developed by Rocketlane Medical Ventures, Uroletics offers a digital health solution for men experiencing urinary incontinence or erectile dysfunction following radical prostatectomy for prostate cancer. The app guides patients through a guideline-based, 3D-supported pelvic floor training program before and after surgery. Additional features include an incontinence and erection analysis, a psycho-oncological coach, a PSA follow-up calendar, and a complication tracker, providing holistic support for recovery and quality of life.
Somnovia | CBT-I program for better sleep
Developed by GAIA AG, somnovia is designed for adults with chronic insomnia unrelated to other medical conditions. The web-based program applies CBT-I (Cognitive Behavioral Therapy for Insomnia) techniques to improve sleep quality and reduce anxiety or depressive symptoms. A randomized controlled trial showed that users of somnovia experienced significantly fewer sleep disturbances after three months compared to standard care alone. The therapy can be used independently, as bridge support while waiting for psychotherapy, or alongside other treatments.
companion shoulder | Digital exercise coach for shoulder health
Developed by medi, companion® shoulder is a browser-based DiGA supporting patients with shoulder lesions (ICD-10: M75). The app offers individualized, guideline-based exercise therapy with video-guided sessions focusing on mobility, strength, and coordination. Exercises adapt to user feedback on pain and strain levels. Educational content, progress tracking, and personalized feedback empower users to manage their rehabilitation and improve shoulder function effectively.
Glucura | Nutrition-based therapy for type 2 diabetes
Glucura is a digital therapeutic that supports the treatment of type 2 diabetes through personalized nutrition and lifestyle modification. Over 90 days, users receive individualized, low-glycemic dietary recommendations based on their personal glucose responses, combined with behavioral strategies to sustainably lower blood sugar levels and improve metabolic health. The program aims to reduce glucose variability, body weight, and HbA1c values. As a non-pharmacological, guideline-based therapy, glucura can be used as a first-line treatment, an alternative to drug escalation, or a complement to existing therapies.

/RootCamp_Logo-Ecosystem.png?width=200&name=RootCamp_Logo-Ecosystem.png)
/Bitroad_Logo-Ecosystem.png?width=200&name=Bitroad_Logo-Ecosystem.png)



/White%20Versions/stadt_leipzig_white.png?width=130&name=stadt_leipzig_white.png)
/lfca_white.png?width=119&name=lfca_white.png)

/White%20Versions/sachsen_signet_white.png?width=65&height=79&name=sachsen_signet_white.png)